Recombinant Human SIGLEC9/CD329 Protein (His Tag)(Active)

Recombinant Human SIGLEC9/CD329 Protein (His Tag)(Active)

SKU #	PKSH033787
Expression Host	HEK293 Cells

Description

Synonyms	CDw329,Protein FOAP-9,SIGLEC9,Sialic acid-binding Ig-like lectin 9,Siglec-9
Species	Human
Expression Host	HEK293 Cells
Sequence	Gln18-Gly348
Accession	AAH35365.2
Calculated Molecular Weight	36.9 kDa
Observed Molecular Weight	55-90 kDa
Tag	C-His
Bio-activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per g of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80. Reconstituted protein solution can be stored at 4-8 for 2-7 days. Aliquots of reconstituted samples are stable at < -20 for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 m filtered solution of PBS, 2mM EDTA, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils); and found in liver; fetal liver; bone marrow; placenta; spleen and in lower levels in skeletal muscle; fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.